The landmark study of human adrenal cortex development began in the 1960s. All kinds of cortical hormones are secreted by epithelial cells of different layers of adrenal cortex: and the globular band cells secrete saline corticosteroids, which are mainly aldosterone the middle zona fasciculata produce glucocorticoids, which are mainly cortisol and the innermost zona reticularis contains a network of cells that synthesize sex steroid hormones such as dehydroandrosterone and estradiol, also secrete a small amount of glucocorticoids. Cortical hormones secreted by the adrenal cortex are classified into three categories, namely, salt corticosteroids, glucocorticoids and sex hormones.
It can be divided into three parts: the zona glomerulosa (zG), the zona fasciculata (zF) and the zona reticularis (zR). The adrenal cortex is thicker and is located in the outer layer of the adrenal cortex, which accounts for about 80% of the adrenal gland. The left adrenal gland is half-moon and the right adrenal gland is triangular.
The adrenal glands are a pair of organs located adjacent to the superior pole of each kidney. The Development of Adrenal Cortical Morphology Abnormal development of the adrenal cortex can lead to metabolic disorders of electrolytes and carbohydrates, leading to circulatory failure, hypoglycemic coma and death.Ģ.1. Therefore, the normal development of the adrenal gland during the fetal period is the key to determine the maturation and destiny of the fetus. Moreover, it is also important for the growth and development of the fetus after birth. It is of great significance to maintain pregnancy and promote fetal growth and nervous system development. As an important endocrine organ of the human body, the adrenal gland is responsible for the synthesis of various steroid hormones. Medulla cells come from nerve ectoderm and cortex comes from mesoderm tissue, which has different physiological functions. It is known that the adrenal glands include outer cortex and inner medulla, which come from different embryonic development layers respectively.
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